Cancer Registration & Surveillance Modules, U.S. Department of Health and Human Services. Melanoma develops when melanocytes undergo malignant transformation. Melanocytes produce the skin coloring or pigment known as melanin, which gives skin its tan or brown color and helps protect the deeper layers of the skin from the harmful effects of the sun. 3 Stem cells are also found in this layer of the skin. What people with cancer should know: https://www.cancer.gov/coronavirus, Get the latest public health information from CDC: https://www.cdc.gov/coronavirus/, Get the latest research information from NIH: https://www.covid19.nih.gov/. The thickness of the epidermis varies in different types of skin; it is only .05 mm thick on the eyelids, and is 1.5 mm thick on the palms and the soles of the feet. The subcutis is also known as the hypodermis or subcutaneous layer, and functions as both an insulator, conserving the body's heat, and as a shock-absorber, protecting the inner organs. We provide a range of services in general dermatology, cosmetic dermatology, skin cancer treatment, and Mohs skin cancer surgery. Sun exposure causes melanocytes to increase production of melanin in order to protect the skin from damaging ultraviolet rays, producing a suntan. The thickness of the epidermis varies in different types of skin; it is only .05 mm thick on the eyelids, and is 1.5 mm thick on the palms and the soles of the feet. This layer contains most of the skins' specialized cells and structures, including: The dermis layer is made up of two sublayers: The upper, papillary layer, contains a thin arrangement of collagen fibers. Eccrine glands are the true sweat glands. The tissue in the hypodermis produces one important cell: At Florida Dermatology and Skin Cancer Centers, our medical professionals are experts in the field of hair, skin, and nails. The subcutis is the innermost layer of the skin, and consists of a network of fat and collagen cells. These glands secrete a milky sweat that encourages the growth of the bacteria responsible for body odor. Your skin shields you from environmental elements, ultraviolet radiation, chemicals, weather conditions, and microbes. It’s the layer of skin where fat is deposited and stored. Within its connective tissues, the dermis produces two important proteins: The hypodermis is made of subcutaneous (under the skin) fats, connective tissues, blood vessels, and nerve cells. Stored fat helps regulate body tissue and cushion your body’s internal organs against bumps, hard impact, and falls. The stratum corneum is the outermost layer of the epidermis, and is made up of 10 to 30 thin layers of continually shedding, dead keratinocytes. Merkel cells, which are tactile cells of neuroectodermal origin, are also located in the basal layer of the epidermis. The Epidermis . 4. 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